Science of TRILOGY

A New Frontier at the Interface of Life and Light

The fastest processes in biology originate from the motion of electrons. The fastest tool available to control them is light. TRILOGY brings these two worlds together by developing the science of ultrafast chirality, where light fields controlled on attosecond time scale interrogate and manipulate the electronic origins of molecular handedness. This frontier connects fundamental quantum science with future biomedical and photonic technologies.

Ultrafast Chirality

Understanding molecular handedness through electron motion on the attosecond timescale. By probing chirality at its electronic origin, we unlock fundamentally new observables and unprecedented sensitivity.

Photoelectron Circular Dichroism (PECD)

Photoelectron Circular Dichroism is one of the most sensitive probes of molecular chirality. When chiral molecules are ionized by circularly polarized light, they emit electrons preferentially in the forward or backward direction, creating a strong enantio-sensitive asymmetry. Unlike conventional chiro-optical techniques, PECD relies on electric-dipole interactions and can enhance chiral sensitivity by orders of magnitude.

Time-Resolved PECD

Time-resolved PECD extends this concept into the ultrafast domain, tracking chiral electron dynamics in real time. It reveals how electronic wave packets evolve, how molecular structure changes after excitation, and how chirality emerges and evolves on femtosecond and attosecond timescales.

Synthetic Chiral Light

Tailored laser fields whose polarization traces a three-dimensional chiral trajectory in time create locally chiral light that couples directly to electronic motion. This allows chirality to be probed through efficient electric-dipole interactions, boosting chiral signals by orders of magnitude compared with conventional optical techniques and enabling new approaches to chiral detection, control, and spectroscopy.

Geometry & Topology in Ultrafast Chiral Dynamics

We explore the geometric structure of ultrafast electron dynamics in chiral matter. Using concepts such as geometric phases and Berry curvature, we reveal how molecular handedness generates topological observables. This framework uncovers the chirality of temporal structures formed by electronic currents and light fields, enabling robust topology-based approaches to chiral spectroscopy and control.

Chiral Biomolecules

From amino acids to nucleic acids and pharmaceuticals, chirality shapes biological function. We develop new methods to reveal molecular structure, folding, and dynamics with ultrahigh sensitivity. Our approaches enable structural characterization of biomolecular ions and their conformational transformations, bridging chiral spectroscopy and next-generation molecular analytics.

Charge and Spin Dynamics

Chiral matter influences the motion of electrons and spins. Understanding these processes is key to emerging concepts in molecular electronics, spintronics, and quantum technologies. TRILOGY investigates how molecular chirality controls ultrafast charge and spin dynamics, revealing the fundamental mechanisms behind chiral-induced spin selectivity and enabling new approaches to spin control with tailored light fields.

Photonic Technologies

We translate discoveries in ultrafast chirality into compact sensing technologies, combining lasers, photonics, microfluidics, and advanced analytics. These platforms bring attosecond science out of the laboratory, enabling scalable, high-throughput chiral sensing through the integration of advanced imaging and miniaturized photonic devices.

Biomedical and Environmental Applications

Applications range from disease biomarkers and pharmaceutical analysis to environmental monitoring, enabling next-generation tools for health, industry, and sustainability.


Open Positions

Doctoral Candidate Projects

TRILOGY recruits 16 doctoral candidates across the network, each pursuing an individual research project with co-supervision and mandatory secondment periods at partner institutions.

DC1

Generation of locally chiral, globally topological light inside optical Quipu fibers

WP3
SKILLS AND CAREER PROSPECTS

Optics, intense light propagation in fibers/wave-guides, structured light, opportunity to participate in experiments and respective experience in fiber optics, and fiber lasers. Excellent prospects both in academia and high-tech industry.

Host: MBI, Germany Secondments: AMP CNR UIBK

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DC2

Ultrafast chiral response and charge directed reactivity

WP1 · WP2
SKILLS AND CAREER PROSPECTS

Training in state-of-the-art table top attosecond sources, fiber laser tech. Applications in advanced photonics, light harvesting, medical and pharma.

Host: UHAM, Germany Secondments: AMP CNRS MBI ULG

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DC3

Chiral photoionization using structured light

WP1 · WP2
SKILLS AND CAREER PROSPECTS

Expertise in core ultrafast technologies (primary and secondary ultrafast sources, attosecond spectroscopy, vacuum technology, particle detection, photoelectron and photoion spectroscopy) as well as in multidimensional data analysis.

Host: CNRS, France Secondments: ICL UHAM WIS AMP

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Before 15/06/26↗
DC4

Theoretical investigation of spin dynamics in strong-field ionization of chiral molecules

WP2
SKILLS AND CAREER PROSPECTS

High performance computing, numerical modeling of non-stationary quantum systems, microscopic & macroscopic. Such skills are in high demand across many physics disciplines and industry, e.g. hydrodynamic flows (aeronautics), straindeformations (medical industry, engineering), etc, and also required skills in IT companies outsourcing ongoing industrial developments.

Host: CNRS, France Secondments: MBI ULG UNK

Closed ↗
DC5

Generation of high rep-rate tunable ultrashort light pulses

WP1 · WP2
SKILLS AND CAREER PROSPECTS

Cutting edge laser technology and applications. Industrial training combined with challenging research application opens wide career opportunities in ultrafast science, engineering, laser applications in biology and medicine.

Host: IOTA/AMP, France Secondments: CNRS UHAM WIS

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DC6

Enantiosensitive dynamics at conical intersections (CI)

WP2
SKILLS AND CAREER PROSPECTS

High performance computing, use of GPUs, methods in electronic structure and quantum dynamics, expertise in modeling chirality, a field of the highest importance for academia, pharma, bio, materials, sensors. Fit for IT sector.

Host: ULG, Belgium Secondments: MBI CNRS UHAM UNIGE

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DC7

Generation of chiral light in nano-devices for optical probes of chiral biomarkers

WP3
SKILLS AND CAREER PROSPECTS

Skills in ultrafast laser sources, femtosecond laser micromachining, ultrafast spectroscopy, material science, data analysis, and vacuum technologies. Excellent prospects with such a skill set both in academia and high-tech industry.

Host: CNR, Italy Secondments: MBI ICL CNRS AMP

Open soon ↗
DC8

All-optical chiral detection with temporally structured light

WP3
SKILLS AND CAREER PROSPECTS

Expertise in ultrafast laser sources, vacuum technology, HHG spectroscopy, advanced data analysis, image processing, and ultrafast science in general are in very high demand in academia and high tech, e.g. laser, industry.

Host: WIS, Israel Secondments: CNRS MBI LU

Open soon ↗
DC9

First principles description of ultrafast charge and spin dynamics in chiral molecules

WP1
SKILLS AND CAREER PROSPECTS

In-depth understanding of electronic structure and ultrafast electron and spin dynamics, expertise in programming, scripting, advanced data processing and artifical intelligence in the natural sciences, intellectual property, project management.

Host: UHAM, Germany Secondments: ULG MBI UoN

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DC10

Design and Micromachining of Microfluidic Devices for Chiral Sensing Applications

WP3
SKILLS AND CAREER PROSPECTS

Skills in femtosecond laser micromachining, materials science, computer-aided design, surface chemistry, fluid dynamics. Excellent prospects with such a skill set both in academia and high-tech industry.

Host: CNR, Italy Secondments: MBI CNRS AMP

Open soon ↗
DC11

Chiral photoelectron spectroscopy of molecular ions

WP3
SKILLS AND CAREER PROSPECTS

Design and operation of complex ion-optical systems, expertise in ultrafast lasers, photoelectron spectroscopy, advanced data processing, analytical and numerical tools for ion and light optics, intellectual property, project management, high vacuum, high voltages. Extremely high demand for such researcher at an instrumentation vendor.

Host: TFS, Germany Secondments: UNIGE MBI FHI UNK SOLEIL

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DC12

Enantiosensitive imaging and manipulation with locally chiral evanescent waves

WP3
SKILLS AND CAREER PROSPECTS

Quantum chemistry, electronic structure, and quantum dynamics in organic molecules, wave propagation in nanophotonic structures, general nanophotonics, nano-fiber design, attosecond molecular physics. High performance computing, use of GPUs, expertise in modeling chirality, a field of the highest importance for academia, pharma, bio, materials, sensors. Fit for IT sector.

Host: ICL, UK Secondments: CNR ULG WIS

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DC13

Chiral RABBITT

WP3
SKILLS AND CAREER PROSPECTS

Analytical and numerical tools to model light propagation, high harmonic generation, attosecond interferometry, reaction microscope, state-of-the-art table-top attosecond sources. These skills are in very high demand in academia, expertise in table top (high harmonic) XUV sources is in very high demand in industry (e.g. ASML).

Host: LU, Sweden Secondments: WIS ICL CNS

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DC14

Developing improved strategies for imaging photoelectron dichroism

WP1 · WP2
SKILLS AND CAREER PROSPECTS

Extensive training in numerical modelling and analysis of big datasets – highly desirable/transferrable skills. Experience in ultrafast lasers, ultra-high vacuum technology, photoelectron imaging, broadly applicable in academia and industry.

Host: HWU, UK Secondments: UHAM CNRS PIT AMP

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DC15

Time-Resolved approaches for transient vibronic chirality

WP2
SKILLS AND CAREER PROSPECTS

Experience in ultrafast lasers, ultra-high vacuum technology, photoelectron imaging and information retrieval, heterodyne detection, coincident detection (electron/ion), non-linear optics, high harmonic generation, UV pulse compression, light polarimetry. High demand in academia and industry.

Host: CNRS, France Secondments: UHAM ULG HWU PIT

Apply here
Before 15/06/26↗
DC**

Enable chiral ion spectroscopy analysis on a high-resolution mass spectrometer

WP1
SKILLS AND CAREER PROSPECTS

Analytical and measurement sciences, expertise in lasers, expertise in mass spectrometry, oligonucleotide and small molecule analysis, advanced data processing, impact on biomedical and pharmaceutical research, intellectual property, project management, high demand in (bio)pharma or instrument manufacturers.

Host: UNIGE, Switzerland Secondments: SOLEIL ULG CNRS MSD

Closed ↗